Working in a histology lab means that I get to see a lot of what our body looks like under the microscope. All images are Copyright © 2015 Della Thomas unless otherwise stated. Most often than not, however, they are asymptomatic. The glands start to appear like deflated balloons or “saw-toothed”, the glandular epithelium become vacuolated as they begin to accumulate glycogen, and the lumen becomes filled with glycogen/glycoprotein secretions. The menstrual phase, which lasts approximately 4-5 days is the initial phase of the menstrual cycle. Tearing of tissue around the compressed glands -. with tubal metaplasia), no nuclear atypia, +/-evidence of shedding (stromal condensation). Part of Springer Nature. In like manner, if the clinical information given the pathologist is incomplete, then he cannot form a clear notion of the clinical problem. Click image for source. "Apoptosis in the human female reproductive tract.". Endometrial histopathology-Basics 1. Usually lasting for just one day, this phase includes a reduction of normal blood supply to the functional layer of the endometrium, which causes ischaemia and necrosis. Low power H&E of endometrium in the secretory phase. Lu KH (April 2009). "Clinical usefulness of endometrial screening by ultrasound in asymptomatic postmenopausal women.". Microscopically, endometrial polyps look almost identical to fragments of endometrium that we have seen above. Click image for source. During this cycle, the endometrium undergoes microscopic changes that can be categorised into four distinct phases. Click image for source. Decide whether you are looking at endometrium. Blue - likely menstrual (stromal condensation). One distinct difference between fragments of endometrium and an endometrial polyp is that the entire structure of a polyp, with the exception of the base, is completely surrounded by surface epithelium: A low power H&E of a portion of endometrial polyp. normal. 178.254.42.8. Sorry, your blog cannot share posts by email. "Endometrial metaplasias and reactive changes: a spectrum of altered differentiation.". So yes, it literally is like having monthly periods in areas of the body that aren’t built to accommodate them. Spencer, SJ. It comprises of two layers; a superficial functional layer that sheds during menstruation, and a deeper basal layer that replenishes the superficial layer once menstruation is complete. The central layer is a thick muscular layer called the myometrium and the outermost layer is a thin slither coating called the serosa (see diagram). Change ), You are commenting using your Twitter account. Symptoms may start as early as the first period but they are often ignored because heavy painful periods are also common at this stage. The ability to detect such functional changes requires not only that the morphologist possess a thorough knowledge of the physiological and pathological anatomy of the endometrium but also that he receive exact information about the patient's menstrual history and have in­ sight into clinical problems. One of the most gruelling pathologies involving endometrium is a (mostly) benign condition called endometriosis. Tightly packed cellular stromal cells known as "stromal condensation". Endometrium in surgical pathology aj 2. This service is more advanced with JavaScript available, Over 10 million scientific documents at your fingertips. 2 Histologie. ; Cataldo, NA. An overview of gynecologic pathology is in the gynecologic pathology article. Another fact about endometriosis is that the ectopic endometrial tissue is completely independent from the uterine lining, exampled by case reports of endometrial malignancies within ectopic endometrial tissue while the uterine lining had remained completely uninvolved and normal. Tightly packed cellular balls of stromal cells with nuclear moulding. Endometrial polyps can occur in a wide range of sizes. Click to share on Twitter (Opens in new window), Click to share on Facebook (Opens in new window), Click to share on Reddit (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on Tumblr (Opens in new window), Click to email this to a friend (Opens in new window), Click to share on LinkedIn (Opens in new window), 2. If they do continue or severity of painful periods increase, it is important to seek medical advice. This cycle of shedding and regeneration, which is at the mercy of hormones and conception, is known as the menstrual cycle and lasts approximately 28 days. During this phase, which lasts approximately 9 days, the endometrium becomes thicker as a result of the stimulatory effect of the oestradiol that is produced by maturing ovarian follicles.

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